Sentence examples for obstruct the pathway from inspiring English sources

"The difficulties which obstruct the pathway to success in flying machine construction," he noted, "are of three general classes".

Short and thick neck would hinder and obstruct the pathway of needle insertion especially when the length of the needle used was quite long as in this case series (Fig.  7f).

β-blockers may also obstruct the NO pathway [ 135].

On the basis of these observations, we conclude that API5, in order to obstruct the proapoptotic pathway, interferes with recruitment of E2F1 transcription factor to target gene promoters such as APAF1.

In granulomatous uveitis, fibrotic tissue and granuloma containing Langhans giant cells accumulate in the trabecular meshwork and Schlemm's canal and may obstruct the filtering pathway created by trabeculectomy.

These chemical constituents might be responsible for inhibiting the catalytic activity of purified human HMG-CoA reductase in a cell-free assay through FPBA extract, and this extract might signify a novel class of HMG-CoA reductase inhibitors that can directly interact with this enzyme to obstruct the mevalonate pathway and prevent hypercholesterolemia.

Thus, BH3 and Smac mimetics can be used to sensitize cancer cells to TRAIL-induced apoptosis by selectively inhibiting important roadblocks that obstruct the TRAIL apoptosis pathway.

Therefore, Weed performed dye injection experiments at pressures of only 9 13 mmHg that also attempted to determine whether or not the injected dye particles themselves could obstruct the normal drainage pathways.

Bradykinin-mediated angioedema commonly affects the lips and tongue, potentially obstructing the oropharyngeal pathway, whereas the nasal passage is unlikely to be obstructed.

Sustained activity of the nodes indicated with red font inside each pathway can (at least partially) restore the pathway's activation and obstruct the effectiveness of PI3K inhibition.

This could obstruct the discovery of important genes and pathways universally involved in meningioma biology.