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There are several obstacles to the effective translation of biomedical discovery into clinical benefit.
Multidrug resistance is one of major obstacles to the effective cancer chemotherapy.
However, the corresponding growth mechanisms remain unclear, which brings obstacles to the effective engineering of the films' properties.
But failure of imagination and the operation of personal bias present obstacles to the effective representation of the interests of others.
It is widely regarded that the endosomal escape barrier is one of the most significant obstacles to the effective use of AOs in therapeutics [92].
We discuss the enablers of and obstacles to the effective use of intermodal transportation in humanitarian logistics and propose future research directions.
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These side effects represent a significant obstacle to the effective treatment of cancer [ 3, 4].
The insistence that focusing on stretches of DNA will ever tell us who we are is an obstacle to the effective study of humans, one that has been fought against for nearly a century by anthropologists and biologists alike.
The lack of this information arguably presents the greatest obstacle to the effective use of conserved genetic resources (FAO 2010; Khoury et al. 2010; Wambugu et al. 2010).
It has long been recognized that the primary obstacle to the effective performance of the probabilistic models is the need to estimate a relevance model.
The organizational and institutional structure which developed under Korean industrial policy became an obstacle to the effective implementation of cooperative R&D.
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