Sentence examples for obstacles in using from inspiring English sources
However, there are still obstacles in using RNAi as an antiviral therapy, particularly for hepatitis C virus (HCV) that displays a high rate of mutation.
We review advances in gene therapy and modelling of the disease using these enzymes and finally, discuss the practical obstacles in using this technology.
However, complex patent issues related to the use of Agrobacterium as a tool for plant genetic engineering and the general requirement of establishing transgenic plants can create obstacles in using this technology for speedy research and development and for agricultural improvements in many plant species.
One of the biggest technical obstacles in using RNAi techniques is that the efficacy of gene silencing varies among different siRNA molecules.
It is widely appreciated that chloroplast DNA has a general advantage of the availability of nearly universal primers that are applicable to entire flowering plants, and less risk of sampling multiple copies from one plant individual, which in turn is one of the major obstacles in using nuclear ribosomal DNA sequences [ 47- 49].
A common obstacle in using such models is how to determine the values of the model parameters.
One obstacle in using these methods is the fact that channels generally occur at multiple scales in the landscape, from small creeks to large rivers.
Decoherence is thought to be a major obstacle in using macroscopic quantum states for quantum computing applications.
In fact, the main obstacle in using such complex and massively parallel DSP processors is the fact that the compilers available today cannot fully exploit the architecture and at the same time achieve efficient code for SDR.
A lack of knowledge is the obstacle in using planning tools rather than the value that small firm managers place on a tool that they have not heard about (Woods and Joyce 2003).
Another obstacle in using macromolecular-based therapeutics is the slow penetration of the drug throughout solid tumors due to sterical hindrance in the extracellular matrix and elevated interstitial fluid pressure resulting in inhomogeneous distribution and low intracellular levels of the drug [39].
