Sentence examples for obstacles in the use of from inspiring English sources

The complexity of many chemical and refining reaction systems and the thus-derived tedious and time-consuming process of building the associated kinetic models have been major obstacles in the use of fundamental kinetics in the solution of chemical engineering problems.

These improvements address major obstacles in the use of biological drugs and will permit multiple dosings in future clinical studies increasing the odds of anti-tumour efficacy.

We highlight some recent progress and discuss several obstacles in the use of expression profiling to identify pathway signatures in human breast cancer.

The presence of IgG1 to Na-APR-1 in sera from humans resident in hookworm endemic areas resolves one of the most critical obstacles in the use of gut antigens as viable targets for vaccines against blood-feeding helminths.

This capability could solve a major obstacle in the use of normal human cells for tissue engineering, that is, the induction of cellular senescence.

The presence of xenogenic GVHD in BLT mice both presents a major obstacle in the use of humanized mice and an opportunity to conduct preclinical studies on GVHD in a humanized model.

The major obstacle in the use of HAART therapy is resistance that virus develops [2].

The major obstacle in the use of lignocellulosic feedstocks is the recalcitrance of the biomass itself.

Additionally, low-abundant transcripts represent another big obstacle in the use of SuperSAGE-based microarrays.

A major obstacle in the use of retinoid therapy in cancer is the resistance to this agent in tumors.

However, one potential obstacle in the use of hNIS for stem cell tracking is gene silencing, which has been reported in neurological studies [ 85].