Sentence examples for obstacles in design from inspiring English sources

Several obstacles in design and control must be overcome to cater for expected industry demands that push the boundaries of existing quadrotor performance.

The blood brain barrier (BBB), systemic cytotoxicity, and limited specificity are the main obstacles in designing brain tumor drugs.

"It turned out to be more complicated than we knew to get just one built," Mr. Rockwell said, referring to a variety of technical obstacles in designing the Burling Slip playground.

The logistical and ethical obstacles in designing such studies (such as blinding multiple drugs or performing multiple sham injections in patients who fail to respond to the first one), however, will make them difficult to execute.

The difficulty and costs of keeping track of a necessarily very large cohort and facilitating follow-up of a sub-sample who become pregnant present major obstacles in designing a study with a capacity to collect information from women immediately preceding and after conception.

A comparative BSA adsorption study proved the lack of non-specific binding, a common obstacle in designing biocompatible nanoparticles.

Motivation: The ability of human immunodeficiency virus-1 (HIV-1) protease to develop mutations that confer multi-drug resistance (MDR) has been a major obstacle in designing rational therapies against HIV.

A major obstacle in designing trials using HIF1 α inhibitors is the length of the study, since many years might elapse prior to reaching the endpoints of CRPC and metastases.

ABSTRACT Sequence diversity and immunodominance are major obstacles in the design of an effective vaccine against HIV.

Like other protein protein interactions, receptor chemokine complexes are considered challenging therapeutic targets for small molecules, and the present structure suggests diverse pocket epitopes that can be exploited to overcome obstacles in drug design.

This paper provides an overview on this subject, aiming at clarifying recent advances and outlining potential challenges and obstacles in building design optimization.