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There is every indication that Frederick valued this relationship, but he increasingly came to see it as an obstacle to securing his imperial rights in northern Italy.
But most NGOs agree the main obstacle to securing good menstrual hygiene for girls is a culture of silence around periods.
Gilmore said: "During the course of this campaign we found that the biggest single obstacle to securing a Yes vote was public fury at the Fianna Fáil government that has brought this country to the brink of economic ruin".
Finance now threatens to become the main obstacle to securing a global climate deal at Copenhagen, following US and Chinese moves last week to provide targets for cuts in their emissions.
The biggest obstacle to securing a deal, she had said then, would be securing funding from advanced nations for developing nations to assist them in carbon reduction.
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The status of the former rebels has been one of the main obstacles to securing a lasting peace since the end of the civil war in 2006.
The institute said nervous employers were reluctant to hire against a backdrop of slack demand, obstacles to securing bank loans and worries about skills shortages.
As Dr. Goosby begins his work in Washington, he faces serious obstacles to securing the full financing Congress has authorized to combat H.I.V. and AIDS — the financing our moral obligations demand.
The demotion of Gove shows that the prime minister will spare nobody – not even close friends – as he removes obstacles to securing a Tory majority at next year's general election.
But despite the negative view of traders and the many political obstacles to securing Opec agreement, some analysts said the fact some of the world's biggest oil producers had managed to overcome their differences to support action was very significant.
There's still a real possibility that the Russians and Syrians are just stalling and will fudge in the end, and even if one or both are serious, there are formidable logistical and political obstacles to securing Syria's chemical weapons swiftly and completely.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.
Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com