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This awareness has been accompanied by international calls to strengthen "systems for recording and updating health worker numbers [that] often do not exist, which presents a major obstacle to developing evidence-based policies on human resources development," such as articulated in the WHO's World Health Report 2006[ 2].
But the state itself is the main obstacle to developing new ventures of all sorts.
Another obstacle to developing a drug-abuse program, Mr. Dale said, is the use of alcohol among young employees.
But a major obstacle to developing villages for tourism, Mr. Ng said, is government restrictions on setting up tourist accommodations.
This has been a major obstacle to developing new treatments and there is currently no effective treatment for rhinovirus infection.
But as with all neurodegenerative disorders, the major obstacle to developing a cure is our current lack of understanding of the disease variation between patients.
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Large volumetric expansion ratio of HFCs is the major obstacle to develop positive displacement expander for HFCs air-conditioning system.
An obstacle to develop 3D concrete has been the lack of tensile strength and therefore, limiting the printed component for structural application.
The immunosuppressive microenvironment induced by growing tumors is a major obstacle to develop active immunotherapeutic approaches for cancer due to its suppression in the protective anti-tumor immunity.
All these impose a huge obstacle to develop a general and automated pathway data curation application, which may readily extract and compile pathway data from these databases.
The major obstacle to develop more robust molecular signatures and better therapies for GBM patients arises from the high intra- and intertumor cellular heterogeneity.
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