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"Time is no obstacle in the search for truth," he said.
Besides, the tissue-specific alternative promoters identified for STAT4 suggest a more complex regulation of the gene, which poses an additional obstacle in the search for the causative variants and their effects.
One central obstacle in the search for such mechanisms is that DR causes a myriad of transcriptional and physiological changes that are either not - or only indirectly - related to its positive effects on lifespan.
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As Jeremy Dean points out at PsyBlog, the implication here is that the benefits of nature might be relatively immune to one of the greatest obstacles in the search for happiness: the hedonic treadmill.
Despite the recent development in radiometric dating of numerous zircons by LA-ICPMS, mineral separation still remains a major obstacle, particularly in the search for the oldest material on Earth.
A big obstacle in your search is the chaos in the ticker symbols.
However, when summarizing methodologies, the first obstacle is the search itself that demanded different strategies and intense manual work.
Yet many of the pages were clearly printed out from computer systems – suggesting that the BBC put an obstacle in the way of easy searching and comprehension of the inquiry.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.
Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com