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That is an incredible waste of effort and money, and a huge obstacle at a time when researchers are developing promising new therapies that must be rigorously tested.
Don't go overboard though; tackle one obstacle at a time.
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Many are relying on family support, sharing cards, details, passwords and PIN numbers in order to get past long-standing obstacles at a time, while the rest of us complain that the latest app isn't quite fulfilling our complex requirements.
For dislocation-solute interactions studied here, TIS is found to be accurate only when the dislocation overcomes multiple obstacles at a time, i.e. jerky motion, and it is inaccurate in the unpinning regime where the energy barrier is of diffusive nature.
His path is strewn with exceedingly dangerous obstacles at a time when the entire region is searching for a model of Arab democracy.
And it bestows fresh salience on relatively abstract features of bulldozers, features a powerful person might credibly share: an ability to take on large tasks, an ability to wear down large obstacles a little at a time, a certain gracelessness in moment-to-moment operation, etc.
Israel will act to remove that obstacle, in a manner, at a time and in a way that will be decided separately".
The prime minister announced he had taken a "leader's call" after a cabinet discussion on Tuesday, arguing the proposed amendments to the Racial Discrimination Act were an obstacle to "national unity" at a time when the government needed community support for major counter-terrorism law changes.
The most likely obstacles might be financial: At a time when France is raising taxes and freezing spending to meet budget targets, an open-ended commitment to a potential financial sinkhole would seem to be a risky proposition.
The Ten of Wands indicates the issue has been a burden for Perry in the past, and he is wary going forward, but, the HPV issue is not an insurmountable obstacle at this time.
Tells about the obstacles he met- buying material at a time when the currency fluctuated hoursly; money transactions with this country are almost impossible; difficulty in finding a place to live; in getting the old factories back; rounding up the workers, and getting production under way.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com