As additional cases accumulate over time, the likelihood of observing cases at specific times is computed with standard methods.
The formal reanalysis included both observed case and last observation carried forward datasets.
Figure 2 Mean change in YMRS total score (with 95% CIs) from baseline (observed case data, ITT set).
Those without observed case results were censored.
We discuss the fully observed case first, and then the partially observed case.
Appendix, Algorithm 1 provides the pseudo-code for the fully observed case.
Nine of the observed case findings took place 'opportunistically' within routine general practitioner (GP) appointments.
Let { q k '}, k ∈ (1, K') be the null set corresponding to the partially observed case.
Appendix, Algorithm 2 provides the pseudo-code of using RJMCMC for the partially observed case.
Different from the fully observed case, the reaction paths at different sub-intervals are now correlated, caused by unobserved species.
The longest observed case of sleep deprivation involved an 18 year old who stayed awake for 264 hours.
