While observing a patient from a healthy state to a diseased state, genomic applications can be used at various crucial checkpoints to personalize the individual's health care [ 34, 35].
14 We have previously observed a 'healthy volunteer effect' in the trial, 15 so the women participating in UKCTOCS may be more health-conscious and aware of medical procedures than the general population, therefore being highly accurate in reporting.
Whereas only mature melanin vesicles can be observed in a healthy postnatal RPE, different stages of melanin vesicle maturation were observed in the cells near monolayer breaks (Fig. 7E, asterisks).
Depletion of Treg from peripheral blood mononuclear cells (PBMC) of CRC patients unmasked CD4+ T cell responses, as observed by IFNγ release, to the tumor associated antigen 5T4, whereas no effect was observed in a healthy age-matched control group.
The reduction in quality of life after a vertebral fracture was 38% lower than that observed in a healthy individual.
Evidence for either direct or indirect immune-mediated rejection of a preleukemic clone has been observed in a healthy monozygotic twin of a child with MLL-rearranged ALL.
As is the case with most laboratory parameters, plasma potassium values are considered as "normal" when they equal those observed in a healthy reference population.
The potential contribution of cortical thinning to the volumetric reductions has recently been added, and reduced middle frontal activity has also been observed in a healthy Met carrier group.
Host-associated microbiota or microbial communities are frequently described as symbionts (Mandel, 2010; Ballal et al., 2011), but this is almost certainly not true for all microorganisms observed in a healthy human.
The prevalence of bimodal gene expression we have observed in a healthy single tissue is approximately 100-times lower than what has been reported in mixed-tissue studies [ 21, 22].
