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We calculated the ratio between QD655 and GFP signals (see Methods) observing a dose response curve.
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Despite observing a dose-dependent increase in risk, this was not statistically significant for the lower two corticosteroid dose treatment groups (Table 2).
Prior studies have also reported a protective effect of ANC on perinatal mortality in both developing and developed countries [ 14, 18, 19], with one observing a dose-dependent association between the number of ANC visits and adverse pregnancy outcomes [ 19].
We observed a dose dependent increase in acetylation on lysine residues of histone proteins extracted from pHCSFs after treatment with ITF2357 (Supplementary figure S2).
By testing 4 different concentrations (range 0.1 10µM) we observed a dose dependant inhibition (Fig. 3A B).
We observed a dose dependent reduction of Smad2 phosphorylation in presence of the inhibitor (Fig. 2B).
We also assessed the effect of SFN on telomerase activity and observed a dose- and time-dependent inhibition in breast cancer cells.
We observed a dose- and time-dependent cell growth inhibition with SFN treatment both in MCF-7 and MDA-MB-231 cells (Fig 1A).
Indeed, we observed a dose dependant accumulation of COUP-TFII mRNA in response to increasing amount of the cAMP analog DiB-cAMP (figure 6C).
Following stimulation of cells with cPAF, we observed a dose- and time-dependent increase in TLR4 gene expression using Real Time PCR analysis (Figure 2a and b).
We observed a dose dependent accumulation of LYL1 after 6 hrs of incubation with increasing concentrations of MG-132 (Fig. 1).
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