Exact(16)
Because these very common side effects may be less likely to reflect target-mediated effects, and in order to prevent them from overwhelming and biasing the downstream analysis, we excluded 27 of the most common side effects (defined as observed with at least 10% of drugs; Supplementary Table 5), after which 1179 side effect types remained.
If all 4 are observed with at least frequency 0.01, a recombination is deemed to have taken place.
More than 2 × 10 unique CpGs were observed with at least 10X coverage in most samples.
This nuclear signal was observed with at least the same intensity in 70% of the breast tumor samples analyzed.
If all four haplotypes are observed with at least a frequency of 0.01, a recombination event between the two markers likely occurred.
In each case, highly efficient gene silencing was observed, with at least 75% silencing of MAP2K4 expression in both cell lines analyzed.
Similar(44)
As discussed below, we propose that this (rapidly attained) surface-binding mode approximates the starting point for the (slow) intercalation process observed with AT-rich DNA through optical measurements.
Two NOx conversion maxima were observed with Pt/TiO2 at 225°C and 350°C operating at 6.6 m s−1.
GFP fluorescence was observed with excitation at 470 nm and emission at 525 nm, CFP with 436/480 nm.
Fragmented, apoptotic, nuclei were observed with excitation at 350 nm, and necrotic nuclei at 530 nm.
Attenuation of the association between age at menarche and diabetes was also observed with BMI at 15 years, but less so with BMI measured earlier in childhood.
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