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Although overlap was observed between the different ETS classes, most of the peaks observed were specific for a given factor, underscoring the specificity of the ETS-family members.
Several control experiments were performed to ascertain whether the effects observed were specific to Pak1 knockdown.
To investigate whether the differences in cytokine secretion observed were specific to mycobacterial antigens, we also studied cytokine and chemokine responses to bacterial lipopolysaccharide (LPS), a strong activator of macrophages.
Finally, the behavioral improvements we observed were specific for the trained target orientation as can be seen from the drop in sensitivity and increase in RT when testing with a non-trained orientation in the control session.
It is noteworthy that PVT-directed treatment did not alter responding on the inactive lever, suggesting that the effects we observed were specific to drug-seeking rather than a generalized reduction in arousal or locomotor activity as a result of CART or TTX infusion.
It is worth mentioning that some of the AS changes observed were specific for each mutant.
Similar(48)
To evaluate whether the effect observed was specific to the NF1-LRD, we transduced NF1-knockdown NNI-21 GPCs with NF1-GRD, NF1-LRD, and pCDH vector and compared their invasive capacities.
The antiviral activity observed was specific, dose-responsive and potent, suggesting that further exploration of PPMO HP1 as a potential HEV-specific antiviral agent is warranted.
With these dramatic effects observed for 68Ga-DOTATOC, a logic question was to verify whether the effect observed is specific for the 68Ga-radiocation, or whether it applies to other trivalent metals used in nuclear medicine as well.
We cannot conclude from the evidence presented here that the Tregs observed are specific for TBHsp70.
Slides were incubated with normal serum alone as a negative control to ensure that any staining observed was specific.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com