Despite the fact that not 100% of the mutant sequences were expected, TALEN-induced GSV was observed to work in a more precise manner after introduction of well designed ssODN.
To depict clearly the brainstem system for micturition control, the present study was designed to record single neuronal activity in the mesopontine tegmentum including the Barrington's nucleus, and to observe its precise timing in relation to bladder contraction recorded simultaneously.
Optogenetics has given researchers unprecedented access to the workings of the brain, allowing them not only to observe its precise neural circuitry in lab animals but to control behavior through the direct manipulation of specific cells.
These results are in sharp contrast to what we observed; the precise overlap produces enhanced GABPα and CREB binding, suggesting that the cooperative binding we observed between the ETS and CREB DNA binding domains is distinct from the cooperative binding observed when full-length proteins are examined.
The present study, in which we used Gsdma KO mice, allowed us to observe the precise expression pattern of Gsdma3 without influence of Gsdma.
Although the library was size-selected for these distributions, we observed very precise boundaries of tRFs (similar to those in miRNA [ 21, 22]), strongly suggestive of a biological process rather than random degradation responsible for their generation.
Gerald Sussman observed that "using precise language to describe essentially imprecise concepts doesn't make them any more precise".
The fabrication of stealth aircraft is inherently unsuited to real assembly-line production - something I learned when I visited the Lockheed Forth Worth plant to observe the infinitesimally precise, hand-labor intensive riveting for the F-22 mid-fuselage section (essential to meet the stealth requirement).
Furthermore, although the amount is less than those caused by large earthquakes, inter-seismic uplift of the mud volcano has also been observed by precise leveling survey at approximately 50 mm (Kusumoto et al. 2014).
Here, we examine the applicability of TLS measurement for an active mud volcano where both gradual and abrupt surficial changes have been observed with precise measurements using the leveling method (Kusumoto et al. 2014, 2015).
