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At longer incubation times (>8 h), small amounts of the HPMA copolymers were observed to enter the cytoplasm and accumulate in the nucleus of the cells.
Indeed the best docked complex in terms of binding free energy supports the model proposed from NMR experiments and the m-difluorophenyl ring of FLZ is observed to enter into the torus cavity of β-CD from the wider end.
As shown in Figure 2b, the GNPs reside in cytoplasm and are enveloped into some vesicles (named 'lick up vesicles'), and no GNPs have been observed to enter into the nucleus.
The AOT-IF was observed to enter the MTN and terminate in the MTNd in parasagittal section (Figure S2, B), whereas the AOT-SF was observed to enter the MTNv where it terminates in both coronal and parasagittal sections (Figure S2, A, B).
During this period, biologically stressful levels of dissolved oxygen were observed to enter the Columbia River estuary from oceanic sources, with minimum values close to the hypoxic threshold of 2.0 mg L−1.
While fish in Papua New Guinea take up to three years to enter freshwater [64] and Queensland fish may not enter until four years of age, fish in the Van Diemen Gulf and the Gulf of Carpentaria were observed to enter freshwater within only one year [62].
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While it would have been impossible, he observes, to enter the mind of Arthur Rimbaud as he wrote "The Drunken Boat" or Mozart as he composed the "Jupiter" Symphony, witnessing the birth of a painting is another matter entirely, especially when time-lapse photography enters the equation.
Last, prostate-specific membrane antigen conjugated QDs specifically targeted prostate tumors in mice (Gao et al. 2004), and QDs complexed with a viral (SV40) nuclear localization signal peptide were observed to readily enter the nuclear compartment of human HeLa cells (Chen and Gerion 2004).
Four of the females found torpid in mating groups were radio tracked and were observed to re-enter hibernation; three of these were later found in mating groups while euthermic and had fresh sperm recovered from their tracts.
Occasionally extracellular Aβ was observed to be entering the cells at the plasma membrane and again these showed co-localization of Aβ and dityrosine labeling.
The rites are observed to some degree before entering a temple, taking part in worship, beginning a festival, or taking out a religious procession.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com