No teams were observed to explicitly consider patient-centred factors in all patient discussions: most teams considered patient-based factors in less than half of cases, mostly comprising demographic information rather than holistic needs or preferences.
Statistical analysis was based on a one-stage Fleming design (P0, success rate ≤8%; P1, success rate ≥23%; type I error = 10%; type II error = 10%), ≥5 successes to be observed to be considered active agent for further investigation.
Three self-fertile Panagrolaimus species/strains (JU765, PS1732, P. detritophagus) were observed to produce sperm – we consider these to most likely be hermaphroditic, though we cannot rule out the possibility that the sperm is only used for egg activation and does not contribute genetic material.
A non-inferiority margin of 0.10 was proposed as the largest difference from 0.90 that could be observed in order to consider the observed agreement non-inferior to the 0.90 assumption.
All the detected patterns of social attachment and influence are observed to be stronger when considering the social subgraph on which communication effectively occurs.
However, we limited our analyses to two orders, linear and quadratic, because the resulting relationships for third order polynomials were observed to be less reliable considering the low number of animals used in this study.
Use of any two concurrent duplicate medications as optimization of monotherapy within a single drug class should be observed prior to considering a new drug class.
There is enough curvature in the response surface and the optimum values are observed to lie within the range considered.
While biomass loading was also known to be a key cost driver, it was further explored in the present study because its impact on the economics of the routes considered was observed to be significantly different.
However, it remains challenging to deal with various uncertainties, accurately to describe correlated events, to accommodate newly observed data and to consider severe accident scenarios within the current framework.
