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HLA class I mediated signaling has been studied, and it was observed that specifically HLA-A2 is substrate for the Alzheimer's disease-associated presenilin-1/gamma-secretase [ 46].
Interestingly, imaging LifeAct-expressing cells over time, we consistently observed that specifically the actively invading cell displayed extensive blebbing early on during invasion followed by the formation of an actin-rich uropod-like structure at the rear of the invading cell.
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Specifically, we observe that post-celebrity suicide content is more likely to be inward focused, manifest decreased social concerns, and laden with greater anxiety, anger, and negative emotion.
It was observed that Irigenin specifically targets the C-C loop of EDA (Fig. 8).
It was observed that HA specifically targeted the chondrocytes as it was primarily found within the lacunae surrounding the cells.
We observed that Nap1 specifically binds to the C-terminal tail of the Rra1 sensor, probably promoting Rra1 protein stability.
Indeed, through an HSE-luciferase gene reporter assay, we observed that MGO specifically increases the transcriptional activity of Hsf-1 (Figure 5C).
We observed that Gab1 specifically bound to PTP1B-D181A mutant, but not by wild type PTP1B.
Of note, we observed that irradiation specifically increases the phosphorylation of SRC kinase protein among SFKs (Fig. 2a).
We observed that UPF1 specifically co-immunoprecipitated with T7-tagged GNL2 in an RNA-independent manner (Supplementary Fig S4).
We observed that Langerin specifically targets LC, which is in contrast to the murine system where also a dermal DC subset is targeted 25.
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