Okada et al (2006) observed resistance development in DOX-resistant clones of osteosarcoma and Ewing's family of tumours after exposure to FK228.
As military chief Helmuth von Moltke observed: "Resistance having nearly always proven useless, the Romanians could no longer think of any other way of defense than flight".
Still, several questions remain about the molecular mechanisms underlying the observed resistance of potato plants [60 62].
These results provide a theoretical basis for explaining experimentally observed resistance of biofilms to chemical disinfectants.
Moreover, observed resistance and reduced efficiency of praziquantel in laboratory strains have prompted the search for alternative therapeutic strategies [20, 21, 22, 23, 24, 25, 26, 27].
The addition of these inhibitors strongly enhanced herbicide phytotoxicity toward R plants, suggesting that metabolic degradation of bispyribac-sodium contributed significantly to the observed resistance.
And fortunately for me the more I observed resistance, the more I was encouraged.
We observed resistance rates of 40.7% to clindamycin and 41.9% to erythromycin among GBS isolates colonizing nonpregnant college students.
The observed resistance to cisplatin in vitro and in primary-tumor derived xenografts was not present for salinomycin.
In the present study, we observed resistance to multiple antimicrobials in E. coli recovered from potable water.
Observed resistance profiles, circulating M. tuberculosis genotypes and epidemiological data on TB patients, were analyzed to ensure a thorough characterization of the cases resulting from drug-resistant isolates.
