Exact(3)
Although we observed proliferating cells in the stromal compartment, the impact of proliferative signalling in the tumour cells is likely to be most relevant to disease course.
Carpelloid development was observed in all C. annuum genotypes tested, which is in agreement with Lippert [ 23] who reported that carpelloid structures are present in a wide range of Capsicum varieties, but are most commonly observed proliferating in accessions with the bell or blocky type of fruit which have an axial type placenta.
The observed proliferating nuclei were in most cases undifferentiated (Figure 3D) or appeared to start to degenerate (Figure 3E), but nuclear structures reminiscent of egg and central cell nuclei were also observed (Figure 3F).
Similar(57)
Such metabolic adaptation observed in proliferating cells is exacerbated in cancer cells, where high rates of unregulated proliferation take place.
Such analog ERK activation was recently also observed in proliferating mammalian fibroblasts [36].
A similar profile, albeit with lower values, was observed for proliferating CD8+ T cells.
This heterogeneous labeling may also explain why discrete peaks were not observed for proliferating cells; subsequent cell division would not lead to equal distribution of the dye among daughter cells.
Using a systematic critical analysis, we show that non-spatial models are not capable of robustly describing the universal statistics observed in proliferating epithelia, indicating strong spatial correlations between cells.
As outlined in Fig. 5, no effect of compound 6c was observed on proliferating cells under these conditions in comparison with the mitogenic effect of epidermal growth factor (EGF) or the antimitotic effect of arabinoside-C (ARA-C).
Cyclin G2 was strongly expressed in the mature keratinocytes localized distally in the hair shaft (arrowheads), whereas the protein was not observed in proliferating keratinocytes in the proximal part of the hair shaft (arrows) at the first anagen stage (Fig. 5E).
Noticeably, a recent paper showed that the differential requirement for Vpr is not due to the cell proliferation status, as infection of arrested T-cells by Vpr HIV-1 reduced viral replication by 2-fold compared to Vpr virus [9], which is essentially the same level of reduction observed in proliferating cells.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com