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Marker loci parameters (map position, number of alleles, observed informative meioses etc).
Despite not being specifically targeted, we observed informative polymorphisms on scA and scB mapping both to FvbPat_4 (4 polymorphisms) and FvbMat_4 (4 polymorphisms) (Table 1, Figure S2, D and K).
As the admixture events occur closer together, this spread in the observed informative wavelet variance decreases.
The frequencies of the observed informative meioses per cross were 0.79 (M × P), 0.72 (W × P) and 0.85 (W × M).
We show that this process creates distinctive patterns in the observed informative variation, which can be used to reconstruct more complex demographic processes (as opposed to being treated solely as a potential source of bias).
Taking into account population size and, hence, the number of observed informative recombinants that conditions the ability to distinguish two linked QTL, a 15 cM exclusionary window on each side of all QTL peaks was applied to refrain from trying to detect too closely linked eQTLs or interpreting large peaks into multiple eQTLs.
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When considering the proximal duplication boundary (∼30.17 Mb), we observed two informative SNPs (30,174,423 and 30,174,589) both of which appear to have been exchanged via crossing over between duplicated and non-duplicated strains.
A frequency of 43% (10 out of 23) and 46% (12 out of 26) LOH was observed in informative ovarian tumours for D8S137 and D8S1048, respectively (Table 2).
A frequency of 33% (four out of 12) and 15% LOH (two out of 13) was observed in informative breast tumours for D8S137 and D8S1048, respectively, with LOH observed for at least one marker in 28% (five out of 18) of the cases (Table 3).
Significant ACC activity was observed following both informative switch and informative repeat cues, but not after neutral cues.
The VC can however observe an informative signal (e.g. 'people skills'),c S t, of the manager's ability in period t at cost c.
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