While at higher concentration (25 μM for HCT116 or 50 μM for SW1116), a marked increase of subdiploid peak was observed, indicating the increase of apoptotic cells.
sAxl is also increased, but it does not follow the two-fold increase observed for Gas6, indicating increased Gas6 signalling during sepsis and related inflammatory conditions.
A statistically significant link between increasing Gleason grade and Ki67LI-gemininLI (P=0.001) was also observed, indicating an increase in the population of cells entering G1 phase in more poorly differentiated tumours.
In this study, a statistically significant link between increasing Gleason grade and Ki67-geminin (P=0.001; Table 1) was observed, indicating an increase in the proportion of cells entering G1.
When concentrations were regressed with river discharge, significant negative relationships observed, indicating that the increased river discharge (from an average 445 m3 s−1 in summer to over 10,744 m3 s−1 in rainy season) reduces metal concentration in rainy season.
In the CAPN3 deficient muscle sections however, nuclear speckle staining can also be observed in myonuclei, indicating increased sumoylation in muscle cells of these patients (Figure S5).
Similarly, the effects of screw rpm and gas pressure on cross-sectional morphology and FTIR spectra were observed indicating an increase in crystallinity.
In the presence of xanthurenic acid at concentration of 10 μM and 20 μM an intensive staining with Calcium Orange™ was observed indicating an increase of free Ca2+ in the cell in a xanthurenic acid concentration-dependent manner (Fig. 7).
In the 1990s, O3 increases at European stations including SNB, CMN, ARO, ZUG/ZSF, and JFJ were broadly observed, indicating that the increasing trend of O3 is a regional-scale phenomenon.
For promoters harboring one, two, and eight tandem operators, corresponding increases in maximal expression were observed (indicating a possible increase in vertical extension, although full response curves were not presented); interestingly, a less-obvious decrease in leakage was also seen.
