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We observed impressive effects of RYGB on diabetes even though our subjects had very severe diabetes.
Although we used a relatively small library size in the present experiments, even in this small library we observed impressive gains in transporter function.
In the present study, investigating vascular effect of metformin treatment during one year, we observed impressive improvement in arterial stiffness in patient with NAFLD treated with metformin.
Nevertheless, we observed impressive disease stabilizations in a number of patients harboring such unfavourable characteristics, and future work should focus on defining features predicting therapeutic efficacy in such patients.
To address this point, we modified the Discussion as follows (see further our response to point 1 above): "Although we used a relatively small library size in the present experiments, even in this small library we observed impressive gains in transporter function.
Nonetheless, we have observed impressive anti-tumour activity of figitumumab in metastatic Ewing's sarcoma as a single agent, with some patients experiencing durable responses up to 3 years, suggesting that targeting IGF-1R alone deserves further evaluation (Olmos et al, 2010b).
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As Mr. Haberman observed, these impressive accomplishments and worthy contributions are routinely passed over by the news and entertainment industries, mesmerized by the likes of a John Gotti or a Tony Soprano.
We observed an impressive upregulation of the mRNA of pro-inflammatory cytokines in animals subjected only to UUO.
We observed an impressive deregulation in the expression of molecules involved in axon growth, guidance and synaptic plasticity.
We observed an impressive increase in total cell counts in the clodronate group at both time points due to compensatory increase in PMNs which caused a higher PMN/macrophage ratio due to depletion of macrophages but increase in PMNs (Figure 7B).
Form the 5th DAP we observed an impressive up-regulation in the self-incompatible combination.
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CEO of Professional Science Editing for Scientists @ prosciediting.com