Exact(3)
The observed functions of Msi proteins in regulation of mammary epithelial cell state mirror the functions we observed in breast cancer cell lines and murine NSCs, and suggest that Msi proteins play similar roles in a healthy in vivo context as in cancer cells.
The observed functions of these two regulatory components also indicate that the insertions of these two TEs did not disrupt the preexisting regulatory functions (losses of function) but rather added new regulatory functions (gains of function).
Our framework is supported by population genetic studies, and it can explain the complete structural evolution of mitochondrial ribosomes and OXPHOS complexes, as well as many observed functions of individual proteins.
Similar(57)
The most easily observed function of LDs, i.e. accumulation of lipids for storage via influx, has been the starting point for attempts to delineate an integrated view of LDs as important organelles for assisting intracellular protein and lipid transport, which includes the mobilization and regulated efflux of lipids [ 5, 6, 30].
No fractures or major complications were observed; good function of the knee was observed.
Connectix engineers then copied the Sony BIOS into the RAM of their computers and observed the functioning of the Sony BIOS in conjunction with the Virtual Game Station hardware emulation software as that hardware emulation software was being developed by Connectix.
Many important and significant changes in the fragmentation patterns were observed as function of both the temperature of photolysis and the context of constitutive activation.
We further observed the function of these fusion proteins in a tumor xenograft mouse model.
We generated tbrd-1 mutant flies and observed that function of tBRD-1 is required for male fertility.
We hypothesized that the differential steady state level of mRNA targets between metastatic and non-metastatic cells might result in this observed dual function of miR-145.
In these we observed specific function of RhoA and ROCK2 but not RhoC and ROCK1 in AA-induced adhesion to BMEC.
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