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HP-induced the de-polymerization of some protein components, together with unfolding and refolding of protein tertiary conformations, partly explaining the observed functionality changes.
We postulate that it is the movement of this fluxional glutamine residue, opening and closing the pore, which conveys the observed functionality.
We then compared the score of each sequence (as determined by the best match to the PWM) against the observed functionality of that sequence.
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Note that the conditional observe implementation also encompasses normal observe functionality.
Based on these requirements, we have chosen to realize this conditional observe functionality by embedding it in the CoAP protocol as a new CoAP option.
CoAP, together with its observe functionality, provides the basis for the integration of constrained devices with the internet at the service level and the realization of embedded web services.
The contribution of this paper is that we present an extension of the CoAP observe functionality that exactly facilitates realizing this behavior by including notification criteria to be specified along with observation request.
In addition, the group designed observe functionality in order to allow a device to publish a value or event to another device that has subscribed to be notified of changes in the resource representation [5].
The failure to observe functionality in some of our asymmetric simulations does not necessarily indicate that the parameters in question must be symmetrical in order for the network to function, as it might be possible to restore functionality by compensatory changes in other parameters in the network.
No main effects of group or group x time were observed on functionality but a significant effect of time was found.
The observed partial functionality of the Mms4-7A variant may be due to its residual phosphorylation, as 12 phosphorylation sites on Mms4 were detected via a mass-spectrometry approach (Matos et al, 2011).
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