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The parameters determining the force laws, are adjusted to fit the experimentally observed force response and the macro- and mesoscale kinematics.
Although the model can reproduce the experimentally observed force variations, correspondence between the model and the actual setup, or the physical background of the model, remains rather unclear compared to JR model explained in the next.
Second, ablating one lateral flank of the amnioserosa reduces the observed force anisotropy and leads to retraction failures.
Do the observed force signatures (force plateaus, spring behaviors) represent the direct mechanical response of type IV pili, or could they also originate from other cell surface components?
The approach trace of the force scan reflects the applied force, which results in the observed force increase on the graph.
To quantify this effect, we measured the melting force at the approximate midpoint of the transition (averaging the observed force over the extension range of 0.44−0.46 nm per base pair).
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He embraced everything from ancient mythology and epic poetry to the keenly observed forces of nature.
Postulations, supported by numerical evidence, have been made about the relationship between the observed forced behaviors and the autonomous characteristics of nonlinear ODE systems.
The applied multiscale coarse-graining (MS-CG) method [ 48] fits observed forces in atomistic simulations by spline functions along a radial mesh connecting atoms.
Consistent with intracellular localization of overexpressed Su48 in cancer cell lines, we have observed forced centrosomal localization of DBZ in primary cultured neurons [ 2].
At a high degree of cross-linking, we observe force plateaus that arise from unzipping, as well as unwinding, of helical bundles.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com