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No important heterogeneity was observed for response rates across subgroups of age, gender, or case/control status (data not shown).
Contrary to what was observed for response to selection for CP, response to selection within pure lines was greater when training was on pure lines although selection was based on GEBVC in all scenarios.
The primary endpoint of the study was PFS-6, but patients were also observed for response to treatment, using a combination of the neurological examination and MRI brain scan to define overall response or progression.
In these trials, using chemotherapy as the comparator, no predictive value of EGFR IHC analysis was observed for response, PFS or survival, and EGFR protein expression status-by-treatment interaction tests were not significant (Fukuoka et al, 2009; Douillard et al, 2010).
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The same progressive trends in visual field organization that were observed for polar angle responses were also observed for responses to stimuli at different eccentricities.
Within the worry condition, responses to probes in the attended location were faster for trials containing threat words than for trials with only neutral words, whereas the converse pattern was observed for responses to probes in the unattended location.
Moreover, responses to the persistent herpesviruses all demonstrated higher activation levels in HIV+ individuals than HIV-, a phenomenon not observed for responses to the non-persistent antigen TT.
A lower level of inter-assay variation was observed for responses that were robustly detected (high/intermediate/low response) compared to low/undetectable responses; mean combined inter-assay %CV was 48.4 ± 7.7 % and 44.4 ± 9.8%% (high/intermediate/low response) and 127.0 ± 1.3 and 58.8 ± 15.0%% (low/undetectable response) for ELISPOT and multimer staining, respectively.
We next examined whether the shifts in response centers observed for suprathreshold responses were also reflected in subthreshold responses.
However, an abnormal response to leptin in OA Ob is likely and resembles what we previously observed for the response to IGF-1.
Higher placebo response rates were observed for ACR20 responses at week 12 in Latin America compared with Europe, North America (see online supplementary table S3).
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