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In 1942 George Orwell observed false propaganda about the Spanish Civil War passing into history, unquestioned, as fact.
A sequence with 38 bp of perfect HMR conservation was statistically significant (280 segments expected, 8031 observed, false positive rate<0.05).
In several established moles, however, we observed false positive staining.
Frequently observed false positive results are troublesome for veterinary authorities and cause financial losses to animal owners.
While false negatives were not observed, false positives (ca. 18%) have no harmful consequence (Springer et al, 2003a).
With some exception [ 5, 32], studies have reported discrepancies between calculated and observed false discovery rates (FDRs) for SFPs.
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In a validation trial of a DNA microarray test for chlamydiae we repeatedly observed false-positive PCR amplicons from truly negative samples and non-template controls.
The inability to differentiate between active and latent TB, limited data on IGRA performance in HIV-infected patients, observed false-negative results, high costs, and logistic problems limit the potential benefit of IGRAs.
The observed false-positive probes were not randomly distributed within probe sets and were clustered.
In Montreal, nine participants were found to be Miriad 'positive' and HCV RNA 'negative'; thus, we also observed false-positive test results for HCV with a concomitant lower specificity, a phenomenon also reported in a recent study by Cha et al. 28 This interesting finding means that these patients were not infected with HCV when they were tested, but may have cleared the virus in the past.
Overall, we did not observe false positive (FP) cases; MRI showed one FN case (one case of DCIS) and galactography 23 FN cases (15 cases of papilloma, 1 case of papillary cancer, 1 case of DCIS, and 6 cases of papillomatosis).
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