Exact(11)
One consequence of the lower observed entry pressures is that solvents are likely to penetrate deeper into the matrix of water-saturated sandstones than previously expected.
When the reagents were used in an equimolar ratios, a reduction in yield was observed (entry 24) and the optimum ratio of 2-methyl-3-trifluoromethylanilin (1) to 2-chloronicotinic acid (2) was 2 1 (entry 21).
Indeed, moderate chirality transfer of >99 1→77:23 e.r. is observed (entry 6).
When we replaced 1 with Selectfluor, fluorination of 2 a was not observed (entry 6).
Reaction time could be successfully shortened to 7 min and no sign of debromination was observed (entry 10) facilitating isolation of compound 6 in 77% of yield.
Only in the case of 4-bromophenol was no conversion observed (entry 2), most likely due to the rather acidic phenolic OH group.
Similar(49)
To ensure that there is no influence on the absorbance caused by the substrates or the enzyme preparations, control reactions of all possible combinations with DCPIP were performed and no decrease in absorbance was observed (entries 1 5).
Several bases were investigated (entries 5 9): using triethylamine or sodium acetate led to full consumption, however debromination was observed (entries 5 and 6).
For electron-neutral arenes, no apparent decrease in the rate of product formation could be observed (entries 1, 3, and 14).
The nature of the alcohol might be expected to have an effect if alkoxide complexation and/or β-hydride elimination is rate-influencing, and indeed a significant variation in product ratio (5 c/ 30 c) was observed (entries 7 10), with methanol leading to enhanced formation of 30 c, but cyclic alcohols reducing the formation of this side product.
Using the calcium indicator dye Fura-2AM, wereere able to observe entry of calcium into Jurkat T cells upon treatment of cells with thapsigargin followed by addition of 2 mM Ca2+ into the extracellular medium (Fig. 2A).
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com