Sentence examples for observed dramatically increased from inspiring English sources

Upon HFD feeding, we observed dramatically increased leptin but normal insulin levels that paralleled the concurrent suppression of lipogenic enzymes in the liver and WAT; on the other hand, abrogation of leptin signaling in db/db mice abolished, at least partially, the suppressing effects of HFD feeding on hepatic ACL and FAS expression.

The apoptosis in HL-60 cells was associated with down-regulation of Bcl-2 and activation of Bax, while in HCT-116 cells, necrotic features were observed; size of cells was dramatically increased by swelling of cytoplasm and loss of membrane integrity, cell rupture and release of cellular contents.

Large differences between the relative amounts of O, Mg, and P were observed after condensation along with dramatically increased relative amounts of C and N, which suggests the successful release of magnesium pyrophosphate and the incorporation of polymer (PLL) during condensation (Supporting Information, Figure S4).

We observed that ΔI3 t) dramatically increases with t up to a characteristic time (≈ 5 and 12 h for P = 25 and 50 MPa, respectively) and then tends to a constant level.

We observed that attempts at closed reduction dramatically increased the puckering pointing to a clenching effect of the muscle on the spiked fragment.

By using MTT and colony formation assays, we observed that overexpression of miR-96 dramatically increased the growth rate of both breast cancer cells as compared with that of negative control (NC) transfected cells (Figure 1C and 1D).

Upon UV irradiation in presence of the ODN, the thermal stabilisation of SRC dramatically increased and we observed increasing restoration of the quadruplex stabilising properties of the ligand over 30 min of irradiation.

Consistent with this report, we observed that the proteasome inhibitor MG132 dramatically increased P-gp levels and apparently abolished the reduction of P-gp levels induced by LY255283 treatment.

Regarding countries with a lower computer adoption rate in 2012, we observe that the percentage of use dramatically increased; for example, from 3%% in 1993 to 73%% in 2012 in Poland, 59 to 82 % in Greece and 34 to 87%% in Latvia.

Interestingly, the dramatically increased caspase activity was observed earlier than for cells expressing intact GFP constructs (Fig. 6C).

In these animals, administration of bleomycin dramatically increased RVSP beyond that observed in WT animals, suggesting that endogenous natriuretic peptides act in an intrinsic defence capacity.