Sentence examples for observed docking from inspiring English sources

In addition, the attachment of the additional rigid substituents at the C-3 position of 1,2,3,4-tetrahydroisoquinoline 1,2,3,4-tetrahydroisoquinolinelectivity, which was consistent well with the obsering docking simulation.

However, h44 in these structures is in different conformations, with its upper portion significantly bent, at varying extents, toward the 50S subunit direction, compared with the mature 30S structure (Fig. S6), indicating that the observed docking of h44 in these structures is probably premature.

The primary SAR study showed that restricting the conformation of the catechol moiety in rolipram with the scaffold of oxazolidinone-fused tetrahydroisoquinoline could lead to an increase in selectivity for PDE4B over PDE4D, which was consistent with the observed docking simulation.

These docking positions constituted 42% of all observed docking sites of OT-GKR.

The observed docked conformation of compound 32 in the mutated protein (I84V) was flipped at ~90°, showed in Figure 6c-d.

Therefore, TIRF-Microscopy provides an ideal tool to observe docking and priming directly [13], [14].

Our simulations results indicate that the initial receptor-ligand interaction observed after docking could be limited due to the receptor rigid docking algorithm and that the conformations and interactions observed after simulation runs are more energetically favored and should be better representations of derivative poses in the receptor.

Our simulation results indicate that the initial receptor-ligand interaction observed after docking can be limited due to the receptor rigid docking algorithm and that the conformations and interactions observed after the simulation runs are more energetically favored and should be better representations of the derivative poses in the receptor.

We also considered whether or not an infrequently observed MAPK docking motif among human proteins could serve as an HIV strain-independent MAPK docking site.

Analyzing the atomic orientations of the 4-amino- substituted inhibitors, we observed that docking on structurally- known ligand-bound bioactive sites is more defined than evaluating random docking.

The ELM Resource describes one version of the D-site (Da), while the current literature contains another frequently observed MAPK docking motif (Db), with a regular expression similar, but not identical, to that of Da [12].