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Several groups have made knock-in mouse models expressing JAK2V617F and have observed divergent phenotypes, each recapitulating some aspects of disease.
We have previously observed divergent phenotypes in MATα and MATa strains lacking the same gene taken from the ORF deletion collection [13], [15].
The observed divergent response of the FoxO transcription factors suggests different functional roles for the specific FoxO members in human skeletal muscle.
Thus, our null finding for MTHFR genotypes and mortality is not at all surprising, and in line with the reports from Anderson (mortality in MTHFR 677TT versus 677CC subjects = 11.7% versus 15.1%, P = 0.62) [17], and from others who observed divergent associations with incident CAD when considering tHcy or the MTHFR 677C→T polymorphism [23].
We observed divergent morphologies in omnivorous fish populations among four shallow lakes.
Consistent with findings of previous studies [ 19, 23], the current study also observed divergent gradients for cigarette and bidi smoking.
Similar(37)
While there is no surprise to observe divergent national strategies because of the unprecedented nature of this catastrophe, the stark contrast between the policies of some states, especially from Eastern Europe, and the rest of the continent now clearly unveils the existence of a dangerous fault line in the European architecture.
We assumed that combined comparison of nucleotide divergence and substitution type observed between divergent species should help to localize "mutation hot-spots" (as measured by nucleotidic diversity upper to %Ti).
The research team observed "markedly divergent responses to heat stress".
Thus, it is of interest to examine whether the occurrence of coding variations in the human population is equally affected by the factors that restrain the substitutions of amino acids observed in divergent evolution of proteins.
Interestingly, we observed such divergent lineages of environmental genes in human microbial gut samples.
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