Sentence examples for observed disruption from inspiring English sources
Ghadially et al. (Ghadially et al., 1983) examined human menisci with electron microscopy and observed disruption or fragmentation and parting of collagen fibrils in the injured portions of torn menisci.
We observed disruption of phagosomal membranes with intrusion of cytosolic material into the phagosome lumen (Fig. S3A) and in some cases bacilli were present in the cytosol without a visible phagosomal membrane boundary, as others reported [14].
We also observed disruption of the inner and outer segments.
In addition, we observed disruption of mitochondrial protein homeostasis following mtDNA truncation or cleavage by CRISPR/Cas9.
In ALS spinal motor neurons as well as TDP-43 depleted neurons, we observed disruption of Gems and abnormal accumulation of U snRNAs/snRNPs.
The earlier observed disruption of cell cell contact between β cells (and therefore function, see Fig. 4E) by α-cell mislocalization could potentially explain such an outcome.
The observed disruptions with the mutant RyR2 described below therefore likely reflect acute atrial arrhythmogenesis rather than representing chronic arrhythmogenic changes following electrical remodeling.
Despite experimental validation of the presence of carbohydrate on residue 110, we failed to observe disruption of dimerization of either the full-length hFSHR or membrane-anchored ECD containing the inserted glycan wedge.
We use Western blotting of LAMP-1 and 2 and exogenous rhodamine-labeled dextran to observe disruption of chloroquine-treated autophagic and phagocytic pathways, respectively.
Because in this study we found no mutations of p53 but did observe disruption of p53 function in transformed HELF cells, the low levels of arsenite apparently induced the dysfunction of p53 via a signal pathway.
We interpret the abnormal cortical structures to arise by the same mechanism as the elongated oocyte spindles that we observe – disruption of microtubule dynamics caused by reduced KLP10A, which reduces the frequency of microtubule catastrophes.
