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Ahier et al. [ 11] and You et al. [ 13] previously used inhibitors specifically designed to bind to insulin receptor-like kinases and observed deleterious effects on the uptake and consumption of glucose by schistosomes, indicating that at least the mechanisms of glucose uptake, similar to Echinococcus as shown in this study, are under the control of insulin signalling in these parasites.
Administration of PO either as a preventative medicine or as treatment significantly improved all the observed deleterious effects induced by CDDP in rat liver and heart.
Intravitally injected QDs were biocompatible and stayed in circulation for over four days without any observed deleterious effects.
Finally, the b alleles, which comprise a small clade of b-like alleles that apparently arose recently in S. invicta, feature a radical, charge-changing substitution (Glu151Lys) that may underlie their observed deleterious effects in homozygous condition [17].
In addition, propranolol was shown to reverse the cognitive impairment induced by stress (Alexander et al. 2007) and acute cocaine withdrawal (Kelley et al. 2007), during which the observed deleterious effects on cognitive performance is believed to be due to noradrenergic upregulation, regardless of task difficulty.
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The observed deleterious effect of stone disease on kidney function was independent of these comorbid conditions.
The observed deleterious effect of kidney stones on kidney function appears to be independent of comorbid conditions.
These assays were also pivotal in obtaining the optimum dose of adenovirus required for efficient transduction of MCF7 breast carcinoma cell line without observing deleterious cytotoxic effects.
(A corollary, peak debt, was coined in 2006 by a former Cisco employee named Jaswant Jain, who calls himself the Prophet of Doom and Gloom, and who first observed the deleterious effects of unrestrained borrowing as an eight-year-old in a village near the city of Jodhpur, where debt-ridden Brahmins appeared worse off than solvent untouchables).
Importantly, we observed no deleterious effects of these drug treatments on the bones of animals.
We did not observe any deleterious effects attributed to riboflavin or UVA irradiation per se during the follow-up, neither in horses with infectious nor aseptic ulcerative keratitis.
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CEO of Professional Science Editing for Scientists @ prosciediting.com