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The maximum observed concentration (Cmax) and the time to Cmax (tmax) were determined directly from the observed plasma concentration time profiles over the 72-h sampling interval.
It is also consistent with the experimentally observed concentration dependence of these reactions.
Multiple population droplet sizes were found to be necessary in order to describe the experimentally observed concentration profile evolution.
The difference of the stress field reveals that the experimentally observed concentration profile can be ascribed to the stress-induced interdiffusion self-limiting effect of the Si nanotips.
tmax, time at maximum observed concentration; Cmax, maximum concentration.
Cp t) was the true concentration, but observed concentration was used during estimation.
Similar(5)
We observed concentration-dependent losses of isoflurane at all stages of solution handling and delivery.
We also observed concentration-dependent performance of skatole-baited traps, in agreement with previously field studies [18].
This initial model was uninformative and showed large differences in predicted vs. observed concentration-time profiles.
Moreover, we observed concentration-dependent increases in lipid accumulation in hepatocytes after treatment with TAB, amiodarone, crizotinib, and sunitinib.
They observed concentration-dependent inhibition in cell cycle machinery, particularly complete inhibition of S-phase progression in MCF7 breast cancer cell line.
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