OQMD is an extensive high-throughput DFT database, consisting of DFT computed crystallographic parameters and formation enthalpies of experimentally observed compounds taken from the Inorganic Crystal Structure Database (ICSD 63 and hypothetical structures created by decorating prototype structures from the ICSD with different compositions.
Interestingly, in our cell model and at the doses we used, we did not observe Compound C-induced phosphorylation of EIF2A as recently reported in different cancer cells [ 41].
It might also be expected that the weakening effect of the lone pair would be observed in compounds of the nitrogen group elements.
Overall, we observed that compounds composed of carbon and phosphorus or carbon and nitrogen were preferentially taken up by the bacterial assemblage as a whole, as compared with those composed solely of carbon (Table 2).
No interferences were observed from endogenous compounds of plasma and other drugs which are commonly co-administered in elderly patients.
For extracted SPE samples and collected POCIS samples, minimal losses have been previously observed for the compounds of interest during frozen storage for 2-3 months (<7%) and up to 20 months (<20%) [61].
The same way, Teixeira et al. [ 30] observed that most compounds of a sample of Brazilian propolis (from Minas Gerais State) were detected throughout a year but their contents varied along the year.
Fortunately, we observed both compounds in most of the pool water concentrates, so it just remained to be determined which specific isomer represented each GC/MS chromatographic peak.
Notably, a similar ranking of the potency of the compounds was observed in terms of inhibition of STAT3 phosphorylation, cancer cell proliferation and clonogenicity.
Moreover, the lattice phonon vibrations below 150 cm−1 differ markedly, indicating that the crystal structures of the βRA solid-state forms are different and also that the solvates are not obviously isostructural as frequently observed if compounds form a series of such adducts.
