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These findings suggest that reduced Smc3 acetylation in the ctf4Δ and chl1Δ cells likely contributes to, but might not fully explain, the severity of the observed cohesion defect.
Our results do not exclude the possibility that levels of PCNA accumulation occurring as replication forks transit cohesion sites lead to the observed cohesion defect of the elg1Δ mutant.
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The results of this correlation are shown in Fig. 3. Figure 3a shows the correlated versus observed undrained cohesion with the values of correlation coefficient (R2), mean absolute deviation (MAD), and root mean square of deviation (RMSD).
More specifically, maternal pessimism about the future coparenting relationship was negatively associated with postpartum observed coparenting cohesion (consisting of cooperation, competition, and family warmth), but only in families with highly reactive infants (r = −.63, p < .05).05
The community planning tradition attempted to incorporate the social cohesion observed in successful organic communities into new areas, assuming that such cohesion came with the provision of successful communities' physical facilities.
Only 63% mps3 ∆ pom152 ∆ cells established cohesion, which is similar to the amount of cohesion observed in mps3 ∆75–150 mutants (64%) (Ghosh et al. 2012).
No statistically significant bias was observed with increasing cohesion level even though the extraction ratio was observed to decline.
The use of supercritical CO2 to generate porous polymeric biodegradable scaffolds significantly improves the cellular compatibility and cohesion observed compared to non-porous counterparts, without substantial loss of mechanical shear strength.
Thus, the cohesion observed at the major satellite region of metaphase chromosomes in wild type MEFs (and in the pericentric heterochromatin regions of other organisms) may not rely on cohesin.
Extended to 3D culture, increased affinity of integrin receptors for substrate could also contribute to the overall increase in aggregate cohesion observed here.
We also found a surprising paucity of heterochromatin near the CENP-A domains of these neocentromeres, which may explain a defect in centromere cohesion observed at the neocentromere.
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