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Results of the computer simulations explain the experimentally observed cell stiffening.
Although accumulation in tumours is observed cell uptake and intracellular drug release have been questioned.
In this article, I have developed mainly a theoretical analysis of the commonly observed cell transport phenomena.
After the addition of BL, we again observed cell wall expansion (Fig. 10A).
A cytotoxic effect of the drug treatments was also observed (cell rounding and nuclear fragmentation).
Two of the most commonly observed cell types in the liver are hepatocytes and liver sinusoidal endothelial cells (LSECs).
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The observed cell-stability at 4°C provides the potential to uncouple the blood draw at the clinical site from MACS Cell Separation, e.g. at a central laboratory.
The model correctly describes folding into a confined space as well as the experimentally observed cell-to-cell variation.
In addition, we also observed cell-type-specific contributions.
We observed cell-surface labeling of sialic acids at 8.5 hpf, during gastrulation.
Based on biophysically-motivated neuron models, we identified mechanisms that account for the experimentally observed cell-intrinsic temperature compensation.
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