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The observers (readers) interact with the observed (author), which changes the final result (the story).
"Freaks are called freaks," observed author James Baldwin, "and are treated as they are treated -- in the main, abominably -- because they are human beings who cause to echo, deep within us, our most profound terrors and desires".
Using all 2,479 SCML2 ERs in 293T-REx, no specific enrichment can be observed (Author response image 1A).
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However, to minimize this observed bias, single author performed the vaginal examination.
We measured photobleaching of the donor Cy3 dye, which has a half time (394 seconds) > 20x longer than the average dwell times of the observed binding events (Author response image 2).
To clarify the origin of observed difference, the authors revised their electrical measurements in terms of conductance instead of resistance and found much less discrepancy.
Based on the observed images, the authors believe that stimulated collagen type I fiber at the moment of collision results in hypertrophy of helicoid patterns and their molecular crystal components are fractioned, being positioned to each side of the bundle fibril axis generating polarization and chirality (Figure 1A, 3D 3F, 4E, 4F, 6A, 6D, 7A, 7B).
It is beyond doubt that the dynamic observed by the authors is the radiation into several ecoptypes starting from a single (pre-evolved) clone.
This idea is similar to an approach that was proposed for active learning [ 46], where instead of just reducing the size of the version space (i.e., the amount of models coherent with observed data) the authors propose to directly optimize a loss function relevant for the task at hand.
From 2013 to 2015, the author closely observed two institutional innovations in a provincial justice bureau.
Different from LDA, ATM incorporates authors by adding one more variable, which is uniformed assigned by a set of authors, an observed set in some corpus.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com