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Here as well there were plausible biological mechanisms to explain the observed associations.
The observed associations were consistent across countries, except for aesthetics.
There was also a significant heterogeneity in the observed associations.
Given the cross-sectional study design, we cannot infer causality in the observed associations.
This is likely conservative since these cases likely decreased the strength of observed associations.
Observed associations may be causal or result from uncontrolled confounds related to family upbringing.
Observed associations between these phenotypes could be because there are common genes that influence them all.
To provide a perspective of observed associations between lifestyle exposures and eye diseases in adults.
However, this study was exploratory and further investigation into the causal nature of the observed associations is recommended.
Finally, the cross-sectional design of the current study limits our ability to determine the direction of the observed associations.
Future studies employing a longitudinal design are needed to better understand the direction of the observed associations.
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