However, we cannot exclude the possibility that the autoimmune response we observed was generated against Nedd5 present in other cellular compartments, such as the nervous system.
Although we cannot prove that all of the 479 SNPs are authentic, it is highly unlikely that more than a tiny minority of the SNPs observed were generated in the test tube.
In previous work with very large pressure injections of CaCl2 it was concluded [33] that the pHi decreases observed were generated largely by mitochondrial Ca2+/H+ exchange with some possible contribution from Ca2+ extrusion.
Moreover, due to the inherent constraints of MEG source reconstruction techniques, it is not possible for us to ascertain whether the single mPFC theta source we observe is generated by a more complex source distribution, such as two generators either side of the midline, although it is consistent with previous human studies (Asada et al., 1999; Ishii et al., 1999).
Despite the difficulty of determiningwhether observed cascades are generated by a real influence effect [16]unlessss performing controlled experiments [17]), the role of influence in social network dynamics is widely recognized,albeit not fully understood.
So far we have assumed observed clusters are generated from complete clusters by excluding missing members, but ICS can also arise where observed clusters are complete in themselves.
In regions of the genes where more variability is observed more probes are generated to cover as much of the variation as possible.
Similar results are observed when data are generated from the Gumbel model.
It is possible that the protective effect of Nav1.1-haploinsufficient forebrain excitatory neurons is only observed when seizures are generated spontaneously or in distinct pathologies, and may partially explain the conflicting results.
The 28 to 30 kDa catabolites of decorin and biglycan we observed are consistent with those generated by MMP-13.
