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Based on this quite striking resemblance, one could speculate whether some of the clinically observed aggravation of radiation on chemotherapy-induced cardiac side effects may result, at least in part, from similar effects of combined radiochemotherapy on cardiac myocytes Ca handling.
All these events were transient, and there was no observed aggravation due to the continuous intake of the placebo and the rosehip tablet in each group.
The observed aggravation of acidosis in the LPS-treated animals could be explained by the induction of sepsis, which has repeatedly shown to decrease ventricular contractility load-independently assessed by pressure-volume loops [ 43– 43].
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60 Patients who observed an aggravation of their acne by food intake exhibited higher IGF-1 serum levels (mean =543.9 ng/mL) compared with those who observed no acne aggravation by food intake (mean IGF-1 =391.3 ng/mL).
Our study suggests that the previously observed acute aggravation of pain may be related to the acute increase in muscle tension immediately after resistance training.
We indeed observed an aggravation of myocardial dysfunction induced by high tidal volume ventilation during LPS-induced lung injury potentially contributing to the death of all rats before the end of the experiment.
In patients with T. gondii and HIV infection, marked decrease in CD4+ T cells has been reported and often there is no significant increase in the antibody titer, as observed during aggravation of infection [ 27].
In contrast, when Lan+ APCs were depleted during the chronic phase of psoriasis-like skin disease on d14 (Fig 4A), we observed severe aggravation of the inflammation, whereas in Lan+ APC-sufficient DKO* mice, the psoriatic phenotype remained relatively constant (Fig 4B).
By relocalizing and repeatedly imaging the same dendritic elements every 3 4 days for a period of two weeks, we observed further aggravation of total spine loss in P301S Tau mice during disease progression: The relative spine density declined to 0.94 ± 0.15 of the initial value, while remaining unchanged in wildtype mice (1.01 ± 0.13; Figure 1e).
184, 185 Burris et al 126 and Jung et al 61 observed an aggravation of acne with increased intake of saturated fat, whereas a higher intake of fish, a nutrient source enriched in ω3-fatty acids, exhibited an acne-protective effect.
Where neutrophil depletion was attempted, the coinfection was so severe that no margin to observe further aggravation was left 35.
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