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On the basis of DFT calculations, the optimal ·OH-mediated mineralization mechanism of flutriafol was revealed, and a series of intermediates were observed accumulated in the degradation process, most significance among which were (2-fluorophenyl) 4-fluorophenyl -Methanonee, phenol, dihydroxybenzenes, benzoquinones, muconic acids, maleic acids, oxalic acids and formic acid.
Thus, the toxins can be observed accumulated on the host intestinal epithelial cells (Fig. 6b).
Ultrastructural studies have observed accumulated vesicular structures, striking absence of lamellar-shaped cristae, impaired mitochondrial dynamics and augmented apoptosis in PHB2-deficient cells [ 1, 23, 68, 69].
As a result, we observed accumulated MRGBP mainly in the nucleus of cancer cells in 20 out of the 27 tumours.
We observed accumulated macrophage/microglia in the infarcted cortex and striatum in both FePro-NSC and control groups, and some of them co-labelled with iron.
This suggests that the effects of these perturbations are not extremely fast, even though they are each tied closely to cellular metabolism; the impacts of these perturbations are best observed accumulated over days.
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For example, dissolved H2O2 can be observed accumulating in pyrite slurries at concentrations relevant to this and other studies (micromolar-range) when the Fe2+ in solution is chelated by EDTA, inhibiting the Fenton reaction [6, 16, 29].
In lamellocytes recovered from control larvae, raised at either 22°C or 29°C, Myospheroid protein was observed accumulating at various places along the cell periphery (Figure 3A, see Detail, arrowhead).
More specifically, Dcp2p is observed accumulating over the course of a few minutes in granules containing ENO2 mRNA.
Instead, the TfR was observed accumulating in vesicles, which were more pronounced in cells infected with the strains translocating EspG (WT or Δ espG + pEspG HA).
While GAT did not localize to ΔinvG mutant Salmonella, GAT was observed accumulating at WT-triggered membrane ruffles during invasion (magnified insets).
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