In this study, observed abnormalities referred to all abnormal toxicological endpoints including retarded development, for example, coagulated eggs, malformation, no extension of tail at 24 hpf, no spontaneous movements within 20 s, no heartbeat, no blood circulation and weak pigmentation, heart sac edema, spine deformation, and hatching rate.
The endocytosis of the remnants might induce the observed abnormalities.
More studies need to be taken up to scientifically establish the link, if any, between the observed abnormalities and disorders in bee hives such as Colony Collapse Disorder (CCD)".
SHB has previously been found to interact with Src-family kinases [8], and loss of such an interaction might contribute to the presently observed abnormalities.
Most frequently observed abnormalities were cells with supernumerary centrosomes (range: 3 11).
In ovarian cancer, KRAS mutations belong to the most frequently observed abnormalities [ 2].
Axial malformations were the most commonly observed abnormalities in both sites (Table 3).
Those investigators observed abnormalities of PTP-α-/ embryonic fibroblasts in migrating into space on cell culture dishes.
The most frequently observed abnormalities were gains and high-level amplifications on chromosomes 17q, 19q and 20q.
There were no grossly observed abnormalities in the offspring and the rate of neonatal deaths was similar in control and DEHP treated groups.
Although the axonal MT cytoskeleton had no obvious morphological defects (data not shown), we observed abnormalities in the distribution of proteins and synaptic vesicles along the nerves.
