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In line with the latter observation, we observed a strong effect of Dohh deletion on early embryonic development in C. elegans and mice.
We observed a strong effect of the POLB A165G and T2133C genotypes on overall survival.
Interestingly, even when SF fibrocytes had differentiated, we observed a strong effect of serum resulting in the rounding up of these cells.
However, we neither observed a strong effect on the HMT activity of the enzyme nor did we see a strong reduction in SU VAR 3 9's ability to repress transcription in a transient reporter assay.
In siKGFR-transfected cultures, we observed a strong effect on mRNA expression (0.133 fold, reduction = 86.7%, P = 0.039), with modest variations in response to the presence or absence of KGF and/or 5-FU.
Besides our findings of c-Fos expression under anxiety-inducing conditions, we observed a strong effect of regular voluntary running on dentate gyrus c-Fos activity in cage controls.
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We also observed a stronger effect for sites with more than one protein bound.
When we excluded this farm from the analyses, we observed a stronger effect of vaccination, which indicated that the effect of vaccination could have been underestimated.
Skelly et al 2002 [ 7] observed a stronger effect of maternal smoking in girls than boys, and our data also suggested this pattern; however Alderman et al (1991) report a stronger effect in boys [ 8].
The Nurses Health Studyy observed a stronger protective effect of plasma 25(OH D on breast cancer risk for women who were 60 years old or older [ 16], whereas the French E3N cohort observed a stronger effect in women who were less than 53 years old at enrollment [ 15].
Although nutlin-3 treatment had no additional effect on cisplatin-induced apoptosis in tumour slices or A2780 cells, we clearly observed a stronger effect on A2780 cell survival with this combination after 4 days (Supplementary Figure 2B).
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