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For example, Kondo et al. [24] characterized the C6 rat tumor cell line in vitro and in vivo and observed a small population of stem-like cells derived from the well-characterized side population.
The results showed that 40% of the imDCs bound the particles, with two populations of cells observed: a small population with high binding (4%; approximately 100-fold higher than background) and a second one with low binding (36%; approximately 10-fold higher than background), (Fig. 2A).
When we used PCR to probe the transposon junctions in isolated transposon mutant colonies, we observed a small population harboring both plasmid- and genomic-transposon junctions, as previously reported [ 35].
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However, we do observe a small population at this locus (e.g., Fig. 1).
In addition we observed a small, unusual population with an approximately 2.7N DNA content.
After one cycle of hypoxia and reoxygenation, we observed a small cell population that survived hypoxia as spherical clusters under hypoxic conditions and that resumed proliferation after reoxygenation.
As in the intact Pitx3-GFP midbrain, we also observed a minor population of small (<10 µm) GFP+ cells that were not immunoreactive for TH (Fig. 5C).
However, they also observed that a small population of cells consistently survived in 3D tissue culture systems.
In type II Neat1 KO mice, Lhcgr and Star expression was dramatically downregulated and Akr1c18 expression was observed in a small population of luteal cells (Fig. 3C).
For PNA FISH method, it was even observed a small increase on Listeria population, which was not visible on cultivability data.
Accordingly, prominent paraspeckle formation is observed only in a small population of cells expressing high levels of Neat1_2 in living animals (Nakagawa et al., 2011).
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