Sentence examples for observed a potent from inspiring English sources

Unexpectedly, we observed a potent suppressive effect of C9433 on NO production and iNOS expression in BMDM co-stimulated with TNFα and IFNγ.

Despite these high levels, we still observed a potent inhibition following Langerin/OVA conditioning (Fig 5D).

We injected this adjuvant intradermally together with Langerin/OVA and observed a potent cytotoxic response, in contrast to imiquimod (Fig 1A).

Although we observed a potent inflammatory response secondary to PAR4-AP, PAR4-/ mice were not available in our laboratory at the time this project started.

We observed a potent inhibition of enzyme activity in the presence of Ag ions at a concentration as low as 25 nM.

We observed a potent antioxidant activity and beneficial effect of the methanolic leaf extract of the plant on isolated hepatic mitochondria [ 21] and recently reported the hypoglycemic effect of its constituent saponins mixture [ 22].

While we observed a more potent binding affinity for Hydroxyflutamide compared to Bicalutamide in the same mutational context, it did not yield an agonist-binding mode within our CETSA HT assays (i.e. Hydroxyflutamide alone did not thermally stabilise AR as observed with other AR agonists).

While the FACS results showed the protein levels of Foxp3 reduced in both groups, we observed a more potent decrease of Foxp3 in control Tregs after siRNA silencing.

Interestingly while vemurafenib PLX-40322) is a selective inhibitor for BRAF V600E, we observed a more potent effect on viability in a mutant HRAS cell line (with wild-type BRAF) than the BRAF V600E cell line, A375, when treated at similar concentrations.

Given that miRNAs often only fine tune their targets by 20%to30%0%, even in ectopic tests, the 13-fold regulation we observed indicates a potent regulatory interaction between miR-92a and  sha.

24 This dual effect of TNF-α, and the fact that both receptors are here shown to be present on the tenocytes, albeit TNF-R1 more distinctively, might explain why we did not observe a more potent negative effect of TNF-α in our results from the cell viability assay.