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Doyle et al. observed a coordinated migration in fibroblasts moving on thin (1D) lines with a width of up to 5 µm [1].
By analyzing the expression profile of protein coding genes and microRNAs in unilineage CB E, MK, G and Mo cultures, at sequential stages of differentiation and maturation, we observed a coordinated, fully interconnected and scalable character of cell population behaviour in both transcriptome and miRNome spaces reminiscent of an attractor-like dynamics.
Using this strategy, we observed a coordinated reduction in the concentration of both complex IV subunits, the silenced nuclear-encoded subunit COX4 as well as the mtDNA-encoded subunit COX1, a few days after transfection (data not shown), indicating that this approach is in principle feasible.
Under paraquat stress, we observed a coordinated and specific response of genes used in regulation of free iron concentration and iron-regulated response: the two ferritin subunits and the iron regulatory protein 1B (irp1B) are overexpressed, while the transferrin 1 (tsf1) gene is severely repressed.
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In addition, we could observe a coordinated Eva1 up-regulation in stromal and haematopoietic cells in coculture control experiments, suggesting a possible EVA1 involvement in TEC-haematopoietic cells crosstalk mechanisms.
Using two different approaches for global pathway analysis, we observed a consistent coordinated up-regulation of genes involved in ribosomal protein biosynthesis in muscle of PCOS patients after pioglitazone administration.
We observed a relationship between the coordinated care and health status by slowing down the rate of functional deterioration and by improving survival time.
It must be remarked that in the case the i th RS observes all coordinated BSs in LOS (hence BS RS link channels are rank deficient) the rank of H i grows up to full-rows rank provided that channels to the B BSs be linearly independent.
Arg213 has previously been observed to undergo a coordinated conformational change upon β8−α8 loop closure.
Among them we observed high coordinated expression levels of genes involved in a) cell communication (KRT4, VWF and COMP); b) epidermal development (KLK7, LAMA3 and EVPL); and c) functionally related to kallikreins (EVPL, KLK6, KLK7, KLK8, SERPINB13, SERPING1 and SLPI).
We observed the coordinated up-regulation of genes involved in photosynthetic and protein biosynthesis and folding pathways in the A and B genomes of allopolyploid wheat.
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