Interestingly, we observed a higher complication rate in patients with a postoperative lactate level >3 mmol/L.
We observed a wound complication rate of 20% in our study, which is similar to series using postoperative EBRT alone [ 27, 31] and compares favourably with series using preoperative EBRT [ 19, 27] indicating that the use of an IOERT boost does not increase the wound complication rate.
Similar results were reported by Innocenti who observed an overall complication rate of 44% in lower limb (twenty-eight out of sixty-six flaps) [ 27].
We observed an overall complication rate of 33% with four cases of superficial epidermolysis that spontaneously healed and three cases of partial flap loss ranging from 10 to 50% that required surgical revision by means of skin graft (two cases) or ALT free flap (one case).
This study evaluated the effects of NSAIDs on HO development and observed a significantly higher complication rate in those patients who did not receive prophylaxis.
Meningoencephalitis was first observed in elderly patients in Israel in 1957 and subsequently observed as a complication in young children in India (6, 7).
In our consecutive 100 cases, we observed a variety of complications known to be associated with the bone transport technique.
Malnutrition is commonly observed as a complication and a strong predictor of mortality in HD patients.
During a hospital stay, pneumonia was more frequently observed as a complication in a late failure group compared to a success group (12.9% vs. 0%) [ 2].
In addition, metabolic acidosis with an enlarged anion gap due to reduced citric acid cycle production of bicarbonate out of citrate and accumulation of negative loaded citrate ions might be observed as a complication of CVVHD using citrate for regional anticoagulation [ 12].
The presence of MPE can be observed as a complication of nearly all malignancies, most frequently lung and breast cancers, whereas pneumonic and tuberculous infections are the leading causes of BPE (Neragi-Miandoab, 2006; Villena-Garrido et al, 2006; Roberts et al, 2010).
