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Brouwer et al. [22] observed a borderline effect of valgus malalignment on the risk of incident OA, while varus malalignment had a larger effect.
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In this regard, we observed a borderline combined effect between these polymorphisms and the risk of lung cancer, as individuals homozygous for both risk genotypes showed a further increase in the risk of developing lung cancer than that observed for the individual polymorphisms (adjusted OR = 2.25; 95% CI 0.83 6.13, P = 0.202).
In the biological model we observed a borderline additive interaction effect on the risk of MI in individuals carrying the haplotype pair 17 as shown by the wide confidence interval relative to the S index; in the statistical interaction model we did observe a significant interaction between the two haplotypes.
In our study, we observed a borderline association.
We observed a borderline (20 30 %) high prevalence of vitamin A, C and E dietary inadequacies.
We additionally observed a borderline dose response relationship between occupational metal dust exposure and laryngeal carcinoma.
Also, we observed a borderline statistically significant inverse association between grilled hamburgers and CRC risk.
This study observed a borderline significant association between these combined genotypes and PRCa risk (RR=3.43; 95% CI=0.999 11.770).
In the same strata we also observed a borderline significant increase in daily rates of all-cause cardiac outcomes (1.07 [0.99–1.07]).
We observed the largest declines for the traffic-related air pollutants NO2, CO, and UFP, but we also observed a borderline significant decline for PM2.5.
After correction by study centre, this association was only observed to display a borderline effect (p = 0.05).
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